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Anthony J. Domma

B.S., Louisiana State University, 2017

Research: This lab has found that HCMV protein UL148 induces quality control structures, and formation of these structures are PERK dependent. My project is to identify the protein-protein interactions that are crucial for the formation of these quality control structures. I will use tandem affinity purification and other methods in attempts to elucidate the molecular mechanism of how 148 induces stress and to answer if its effects on Endoplasmic Reticulum Associated Degradation (ERAD) are specific.